https://www.sabrakleinlab.org/home daily 1.0 2025-12-29 https://www.sabrakleinlab.org/research daily 0.75 2024-06-11 https://images.squarespace-cdn.com/content/v1/5f0b9888f8ecf44ed894ed63/1595298926395-4CGUVAJKNVADKDGSLVPD/zika Research https://images.squarespace-cdn.com/content/v1/5f0b9888f8ecf44ed894ed63/1595298067873-LP2O6ECGZS1BFJPKTDZ7/vaccination.png Research https://images.squarespace-cdn.com/content/v1/5f0b9888f8ecf44ed894ed63/1595297921468-NTMV1PE04EIIUNLQGP0B/Influenza.png Research https://images.squarespace-cdn.com/content/v1/5f0b9888f8ecf44ed894ed63/1595299867942-72DJCFYJNMSNFZF1KZXK/covid.png Research https://www.sabrakleinlab.org/news daily 0.75 2025-12-29 https://www.sabrakleinlab.org/contact daily 0.75 2020-08-03 https://www.sabrakleinlab.org/people daily 0.75 2025-12-29 https://images.squarespace-cdn.com/content/v1/5f0b9888f8ecf44ed894ed63/598b47f2-ea90-40b1-9c54-cfeeef51aa04/_JHU4569.jpg People - Sabra L. Klein, PhD – Professor and Lab Head Publications | Email | LinkedIn | Wikipedia Dr. Klein’s primary appointment is in the Department of Molecular Microbiology and Immunology, with joint appointments in the Departments of Biochemistry and Molecular Biology and International Health, at the Johns Hopkins Bloomberg School of Public Health and the Department of Medicine in the Division of Infectious Diseases at the Johns Hopkins School of Medicine. She also participates in the Cellular and Molecular Medicine Program and Immunology Graduate Program at the Johns Hopkins School of Medicine. She is an expert on sex and gender differences in immune responses and susceptibility to infection and currently has over 150 peer-reviewed publications, authored several book chapters, and edited three books on the broad topics of sex differences in response to infection and treatments for infectious diseases. During the 2009 influenza pandemic, she was commissioned by the WHO to evaluate and publish a report on the impact of sex, gender, and pregnancy on the outcome of influenza virus infection. During the COVID-19 pandemic, Dr. Klein wrote commentaries for several journals and was interviewed by several major news media outlets about male-biased disease outcomes. She is co-director of the Johns Hopkins Center for Women’s Health, Sex, and Gender Research, MPI for the Johns Hopkins Building Interdisciplinary Careers in Women’s Health (BIRCWH), and a fellow of the American Academy of Microbiology and American Academy for the Advancement of Science. https://images.squarespace-cdn.com/content/v1/5f0b9888f8ecf44ed894ed63/315b770d-2079-408a-867a-d194ee349918/Headshot.JPG People - Rishi Pandey – ScM student, Molecular Microbiology & Immunology Email | LinkedIn Rishi completed his BS in Biochemistry at the University of Maryland, College Park. Here he worked in the lab of Dr. Kyungjin Yoo as a CS research fellow, developing a Virtual Reality program which modernized museum attractions. He also worked as a COVID Research Assistant at a local clinical pathology lab during the pandemic. After graduating, Rishi worked as a Vaccine R&D Associate Scientist at Pfizer. Here he performed clinical immunoassays in high-containment BSL-3 labs, aided in assay validation, and served as the SME for multiple machines and processes. In the Klein lab, he is interested in studying the effect of viral infection on pregnancy via Systems Serology under the guidance of Maclaine. Outside of the lab, Rishi enjoys playing tennis, lifting, eating, playing computer games, watching K-dramas, and sleeping. https://images.squarespace-cdn.com/content/v1/5f0b9888f8ecf44ed894ed63/31d6b1bf-12f1-43d1-ad93-559a8fd540b2/Anna.jpg People - Anna Yin, MPH, Data Analyst Publications | LinkedIn Anna obtained her BS in Microbiology from the University of Michigan and her MPH in Biostatistics and Epidemiology at the Johns Hopkins Bloomberg School of Public Health. She previously worked as a research associate in the labs of Drs. Daniel H. Geschwind and Jessica E. Rexach where she used a systems biology approach in human, mouse, and iPSC-derived spheroid models to elucidate the genetic and neuroimmune signaling pathways involved in neurodegenerative dementias. In the Klein lab, Anna is interested studying how patient demographics, especially sex and age, modify SARS-CoV-2 disease severity and durability of humoral immunity. Anna is passionate about intersecting biological research and biostatistical analyses to better understand infectious disease pathogenesis and inform vaccine development. https://images.squarespace-cdn.com/content/v1/5f0b9888f8ecf44ed894ed63/8702fc6f-cd61-4492-9a33-4bbf6affe4e3/IMG_7416+4.jpg People - Brittany Siebert, MSc, PhD – Postdoctoral Fellow Publications | Email | LinkedIn Brittany completed her B.S. in Animal Biology and M.Sc. in Avian Biology at the University of California, Davis. During this time, she worked on examining the epidemiological characteristics of the zoonotic bacteria Chlamydia psittaci in wild birds across California. She acquired experience working in classical clinical bacteriology techniques and analysis of epidemiological data. She then joined Dr. Daniel Perez’s lab at the University of Georgia, where she earned her Ph.D. in Comparative Biomedical Sciences in the Department of Population Health. Her research focused on testing new reverse genetics vectors for the rescue of influenza A and B viruses, constructing in vitro and in vivo model systems to study aerosol transmission of influenza A viruses (H1N1, H3N2, and H9N2), and characterizing changes in the respiratory and intestinal microbiota during respiratory viral infections (influenza A virus and SARS-CoV-2). In the Klein lab, Brittany is interested in using molecular and bioinformatic tools to explore the relationship between respiratory viral pathogens, the immune system, and the residential host microbiota that contribute to differences in disease pathogenesis in biological sex and pregnancy. Outside of the lab, Brittany enjoys traveling, concerts, playing with her dogs, cooking, and baking. https://images.squarespace-cdn.com/content/v1/5f0b9888f8ecf44ed894ed63/413a5ca8-65ec-49bc-a889-54ff543ff530/Jenn.jpg People - Jennifer Liu, PhD – Postdoctoral Fellow Publications | Email | Twitter | LinkedIn Jennifer A. Liu earned her B.S. in Biology minoring in Chemistry and Healthcare Ethics at Utica College (Utica University) where she gained experience working in an ecology research lab looking at circadian rhythm disruption and light pollution in amphibians. She joined Dr. Randy Nelson's lab in the Department of Neuroscience in the Rockefeller Neuroscience Institute in the School of Medicine at West Virginia University where she earned her Ph.D in Neuroscience. Her research at WVU focused on characterizing neuroimmune changes in the brain that resulted in increased neuronal injury and death following ischemic injury with exposure to light at night. Additionally, her other aim of research from her dissertation sought to investigate the influences of chronic circadian disruption altering physiological function including physiological aging, immune response, and cerebrovascular changes that correspond to cognitive impairments and dementia in aged mice. In the Klein lab, Jennifer is interested in characterizing sex differences in cognitive function and neuroimmune cross-talk following acute pathogenesis and post-acute sequelae in a rodent model of SARS-CoV-2. Outside of lab, Jennifer enjoys movies, board games, and trying new restaurants. https://images.squarespace-cdn.com/content/v1/5f0b9888f8ecf44ed894ed63/688671d1-7fb2-4bb7-877d-b67074238006/Maclaine.jpg People - Maclaine Parish – PhD Candidate, Cellular and Molecular Medicine Publications | Email | LinkedIn Maclaine completed her BS in Molecular, Cellular and Developmental Biology with a minor in Spanish at the University of Michigan in 2022. Here she worked in the lab of Dr. Anthony Antonellis studying the molecular mechanisms driving peripheral neuropathies in patients with tRNA synthetase mutations. She also worked in the lab of Dr. Dwayne Stupack at UCSD studying high grade serous ovarian cancer; an experience that solidified her interests in women’s health research. In the Klein lab, Maclaine is interested in understanding how viral infections interfere with healthy pregnancies, resulting in adverse maternal and fetal outcomes. This encompasses human clinical trial work studying SARS-CoV-2 vaccine responses in pregnant people in addition to utilizing mouse models of Influenza A Virus infection during pregnancy. Outside of lab, Maclaine enjoys traveling, hiking, cooking and running. https://images.squarespace-cdn.com/content/v1/5f0b9888f8ecf44ed894ed63/1595898372012-UI7R2TFYDO30M94NF5TM/Han-Sol.jpg People - Han-Sol Park, PhD – Senior Research Associate Publications | Email | Twitter | LinkedIn Dr. Park received her Ph.D. and M.S. in medical science from University of Ulsan, Seoul, South Korea. She holds a B.S. from Kangwon National University, Chuncheon, South Korea. Dr. Park joined as a research associate in Dr. Klein’s lab in 2019. She manages the centralized immune response core for the Johns Hopkins Specialized Center of Research Excellence in Sex Differences and the serology cores for the Johns Hopkins Center of Excellence in Influenza Research and Surveillance and the Johns Hopkins COVID-19 Convalescent Plasma Studies. During the current COVID-19 pandemic, Dr. Park has developed a sensitive ELISA to detect COVID-19 antibodies in human convalescent plasma. Her expert knowledge and skill in flow cytometry and serology assays have been vital for both COVID-19 and influenza vaccine projects. Prior to joining Dr. Klein, Dr. Park worked as a research fellow (2016 -2019) with Dr. Patricia Gearhart (NIA, NIH) exmining specific B cell populations under different immunological and inflammatory disease models. Dr. Park was also a visiting fellow (2014 – 2016) at Dr. Li Lin’s lab (NIA, NIH) where she investigated intracellular signaling mechanisms involving membrane receptor-ligand interaction. https://images.squarespace-cdn.com/content/v1/5f0b9888f8ecf44ed894ed63/1634662212905-PRPHSG7WNKH02UC67MVL/Sabal.jpg People - Sabal Chaulagain, BVSc&AH, PhD – Postdoctoral Fellow Publications | Email | Twitter | LinkedIn Sabal Chaulagain earned his Bachelor of Veterinary Science and Animal Husbandry (BVSc & AH, 2013) degree from Tribhuvan University, Nepal. He joined Dr. Daniel Rock’s lab in the department of Pathobiology at the University of Illinois at Urbana-Champaign (UIUC), USA as a visiting scholar (2015) and later obtained his PhD from Dr. Rock’s lab in 2021. His thesis focused on establishing the role of African swine fever virus (ASFV) CD2v protein in NF-κB mediated IFN-β induction leading to apoptosis in lymphocytes and macrophages with an aim to provide explanation for critical ASF disease pathogenic mechanism. He is interested in studying the immune responses and pathogenesis of diseases caused by influenza A/B viruses, SARS-CoV-2, and Zika viruses. In the Klein lab, Sabal is studying the molecular mechanisms of sex differences in influenza B virus pathogenesis. Outside of the lab, he enjoys running, dancing, playing tennis, cooking, watching movies, traveling, and making new friends. https://images.squarespace-cdn.com/content/v1/5f0b9888f8ecf44ed894ed63/da19e5a7-e94a-4ed0-b792-1c98641960fe/Image.jpg People - Karly Shi — Undergraduate Assistant Karly is an undergraduate student at Johns Hopkins University studying molecular and cellular biology. She joined the Klein lab as an undergraduate assistant to learn more about how textbook knowledge applies to laboratory research and how genetics and hormones play into various immune responses, and she's learned a lot through working with Dr. Liu! In her free time, she enjoys making music, reading, and binging audiobooks. https://images.squarespace-cdn.com/content/v1/5f0b9888f8ecf44ed894ed63/37612a6b-e087-4efe-b714-28fbc1947349/DSC03843_Original.jpg People - Emily Watters – ScM student, Molecular Microbiology & Immunology Publications | Email | LinkedIn Emily earned a BS in Microbiology from the Ohio State University in 2024. At Ohio State, she developed a strong interest in immunology and virology. As a result, she joined the Zhu Lab and researched the regulation of HIV-1 viral persistence and how epigenetic markers may be exploited as cure strategies. In the Klein lab, Emily is interested in sex differences in response to influenza in mice. Outside of the lab, Emily enjoys going to concerts, planning trips, and wandering.